Efficient Golgi Forward Trafficking Requires GOLPH3-Driven, PI4P-Dependent Membrane Curvature

Vesicle budding for Golgi-to-plasma membrane trafficking is a key step in secretion. Proteins that induce curvature of the Golgi membrane are predicted to be required, by analogy to vesicle budding from other membranes. Here, we demonstrate that GOLPH3, upon binding to the phosphoinositide PI4P, ind...

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Udgivet i:Dev Cell
Main Authors: Rahajeng, Juliati, Kuna, Ramya S., Makowski, Stefanie L., Tran, Thuy T.T., Buschman, Matthew D., Li, Sheng, Cheng, Norton, Ng, Michelle M., Field, Seth J.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583631/
https://ncbi.nlm.nih.gov/pubmed/31231041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.05.038
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