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Acetate Mediates Alcohol Excitotoxicity in Dopaminergic-like PC12 Cells

Neuronal excitotoxicity is the major cause of alcohol-related brain damage, yet the underlying mechanism remains poorly understood. Using dopaminergic-like PC12 cells, we evaluated the effect of N-methyl-d-aspartate receptors (NMDAR) on acetate-induced changes in PC12 cells: cell death, cytosolic ca...

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Detalhes bibliográficos
Publicado no:ACS Chem Neurosci
Main Authors: Chapp, Andrew D., Behnke, Jessica E., Driscoll, Kyle M., Fan, Yuanyuan, Hoban, Eileen, Shan, Zhiying, Zhang, Li, Chen, Qing-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583493/
https://ncbi.nlm.nih.gov/pubmed/30247872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.8b00189
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