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Polyamidoamine Dendrimer Grafted with an Acid-Responsive Charge-Reversal Layer for Improved Gene Delivery
We report on a heterogeneous dendrimer (G3-acetal-NH(2)) derivative possessing an acid-responsive charge-reversal layer. The synthesis of G3-acetal-NH(2) starts with a polyamidoamine (PAMAM) G3 core and follows the aza-Michael addition with N-(2-(1-(allyloxy)ethoxy)ethyl)acrylamide (AEEAA) synthesiz...
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| Publicado no: | Biomacromolecules |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7583228/ https://ncbi.nlm.nih.gov/pubmed/32820887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biomac.0c00580 |
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