Establishing a Framework for the Clinical Translation of Germline Findings in Precision Oncology

Inherited genetic variation has important implications for cancer screening, early diagnosis, and disease prognosis. A role for germline variation has also been described in shaping the molecular landscape, immune response, microenvironment, and treatment response of individual tumors. However, ther...

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Veröffentlicht in:JNCI Cancer Spectr
Hauptverfasser: Dixon, Katherine, Young, Sean, Shen, Yaoqing, Thibodeau, My Linh, Fok, Alexandra, Pleasance, Erin, Zhao, Eric, Jones, Martin, Aubert, Geraldine, Armstrong, Linlea, Virani, Alice, Regier, Dean, Gelmon, Karen, Renouf, Dan, Chia, Stephen, Bosdet, Ian, Rassekh, S Rod, Deyell, Rebecca J, Yip, Stephen, Fisic, Ana, Titmuss, Emma, Abadi, Shirin, Jones, Steven J M, Sun, Sophie, Karsan, Aly, Marra, Marco, Laskin, Janessa, Lim, Howard, Schrader, Kasmintan A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
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Commentary
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583151/
https://ncbi.nlm.nih.gov/pubmed/33134827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jncics/pkaa045
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