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Weak Ultraviolet B Enhances the Mislocalization of Claudin-1 Mediated by Nitric Oxide and Peroxynitrite Production in Human Keratinocyte-Derived HaCaT Cells

A tight junction (TJ) makes a physical barrier in the epidermal cells of skin. Ultraviolet (UV) light may disrupt the TJ barrier, but the mechanism has not been well clarified. Weak UVB (5 mJ/cm(2)) caused mislocalization of claudin-1 (CLDN1), a component of the TJ strand, and disruption of TJ barri...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kobayashi, Mao, Shu, Shokoku, Marunaka, Kana, Matsunaga, Toshiyuki, Ikari, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583049/
https://ncbi.nlm.nih.gov/pubmed/32992650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197138
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