Constitutive Activation and Inactivation of Mutations Inducing Cell Surface Loss of Receptor and Impairing of Signal Transduction of Agonist-Stimulated Eel Follicle-Stimulating Hormone Receptor

In the present study, we investigated the signal transduction of mutants of the eel follicle-stimulating hormone receptor (eelFSHR). Specifically, we examined the constitutively activating mutant D540G in the third intracellular loop, and four inactivating mutants (A193V, N195I, R546C, and A548V). T...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Byambaragchaa, Munkhzaya, Kim, Jeong-Soo, Park, Hong-Kyu, Kim, Dae-Jung, Hong, Sun-Mee, Kang, Myung-Hwa, Min, Kwan-Sik
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583038/
https://ncbi.nlm.nih.gov/pubmed/32992880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197075
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