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Sericin-Induced Melanogenesis in Cultured Retinal Pigment Epithelial Cells Is Associated with Elevated Levels of Hydrogen Peroxide and Inflammatory Proteins

We previously demonstrated that the silk protein sericin promotes pigmentation of retinal pigment epithelium (RPE) by activating the NF-κB pathway. Among numerous agents, NF-κB can be activated by hydrogen peroxide. In the present study, we explored possible associations between reactive oxygen spec...

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Bibliografische gegevens
Gepubliceerd in:Molecules
Hoofdauteurs: Khan, Ayyad Zartasht, Jackson, Catherine Joan, Utheim, Tor Paaske, Reppe, Sjur, Sapkota, Dipak, Olstad, Ole Kristoffer, Thiede, Bernd, Eidet, Jon Roger
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582875/
https://ncbi.nlm.nih.gov/pubmed/32987810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25194395
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