Sericin-Induced Melanogenesis in Cultured Retinal Pigment Epithelial Cells Is Associated with Elevated Levels of Hydrogen Peroxide and Inflammatory Proteins

We previously demonstrated that the silk protein sericin promotes pigmentation of retinal pigment epithelium (RPE) by activating the NF-κB pathway. Among numerous agents, NF-κB can be activated by hydrogen peroxide. In the present study, we explored possible associations between reactive oxygen spec...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Khan, Ayyad Zartasht, Jackson, Catherine Joan, Utheim, Tor Paaske, Reppe, Sjur, Sapkota, Dipak, Olstad, Ole Kristoffer, Thiede, Bernd, Eidet, Jon Roger
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582875/
https://ncbi.nlm.nih.gov/pubmed/32987810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25194395
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