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Huisgen [3 + 2] Dipolar Cycloadditions of Phthalazinium Ylides to Activated Symmetric and Non-Symmetric Alkynes

We present herein a straightforward and efficient pathway for the synthesis of pyrrolophthalazine cycloadducts via Huisgen [3 + 2] dipolar cycloaddition reactions of phthalazinium ylides to methyl propiolate or dimethyl acetylenedicarboxylate (DMAD). A thoroughly comparative study concerning the eff...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Antoci, Vasilichia, Moldoveanu, Costel, Danac, Ramona, Mangalagiu, Violeta, Zbancioc, Gheorghita
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582813/
https://ncbi.nlm.nih.gov/pubmed/32992961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25194416
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