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Opposites Attract: Escherichia coli Heptosyltransferase I Conformational Changes Induced by Interactions between Substrate and Positively Charged Residues

Gram-negative bacterial viability is greatly reduced by the disruption of heptose sugar addition during the biosynthesis of lipopolysaccharide (LPS), an important bacterial outer membrane component. Heptosyltransferase I (HepI), a member of the GT-B structural subclass of glycosyltransferases (GTs),...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Cote, Joy M., Hecht, Cody J. S., Patel, Kaelan R., Ramirez-Mondragon, Carlos A., Sham, Yuk Y., Taylor, Erika A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582807/
https://ncbi.nlm.nih.gov/pubmed/32011131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b01005
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