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Nucleophilic Synthesis of 6-l-[(18)F]FDOPA. Is Copper-Mediated Radiofluorination the Answer?

Positron emission tomography employing 6-l-[(18)F]fluoro-3,4-dihydroxyphenylalanine (6-l-[(18)F]FDOPA) is currently a highly relevant clinical tool for detection of gliomas, neuroendocrine tumors and evaluation of Parkinson’s disease progression. Yet, the deficiencies of electrophilic synthesis of 6...

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Bibliografski detalji
Izdano u:Molecules
Glavni autor: Krasikova, Raisa N.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582790/
https://ncbi.nlm.nih.gov/pubmed/32977512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25194365
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