High Mannose N-Glycans Promote Migration of Bone-Marrow-Derived Mesenchymal Stromal Cells

For hundreds of indications, mesenchymal stromal cells (MSCs) have not achieved the expected therapeutic efficacy due to an inability of the cells to reach target tissues. We show that inducing high mannose N-glycans either chemically, using the mannosidase I inhibitor Kifunensine, or genetically, u...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Alonso-Garcia, Vivian, Chaboya, Cutter, Li, Qiongyu, Le, Bryan, Congleton, Timothy J., Florez, Jose, Tran, Victoria, Liu, Gang-Yu, Yao, Wei, Lebrilla, Carlito B., Fierro, Fernando A.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582662/
https://ncbi.nlm.nih.gov/pubmed/33003435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197194
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