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Mechanisms of Deamidation of Asparagine Residues and Effects of Main-Chain Conformation on Activation Energy
Deamidation of asparagine (Asn) residues is a nonenzymatic post-translational modification of proteins. Asn deamidation is associated with pathogenesis of age-related diseases and hypofunction of monoclonal antibodies. Deamidation rate is known to be affected by the residue following Asn on the carb...
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| 發表在: | Int J Mol Sci |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
MDPI
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7582646/ https://ncbi.nlm.nih.gov/pubmed/32987875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197035 |
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