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Prolonged Lipid Accumulation in Cultured Primary Human Hepatocytes Rather Leads to ER Stress than Oxidative Stress

Overweight has become a major health care problem in Western societies and is accompanied by an increasing incidence and prevalence of non-alcoholic fatty liver disease (NAFLD). The progression from NAFLD to non-alcoholic steatohepatitis (NASH) marks a crucial tipping point in the progression of sev...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Rennert, Christiane, Heil, Theresa, Schicht, Gerda, Stilkerich, Anna, Seidemann, Lena, Kegel-Hübner, Victoria, Seehofer, Daniel, Damm, Georg
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582586/
https://ncbi.nlm.nih.gov/pubmed/32993055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197097
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