Proteomic Analysis of KCNK3 Loss of Expression Identified Dysregulated Pathways in Pulmonary Vascular Cells

The physiopathology of pulmonary arterial hypertension (PAH) is characterized by pulmonary artery smooth muscle cell (PASMC) and endothelial cell (PAEC) dysfunction, contributing to pulmonary arterial obstruction and PAH progression. KCNK3 loss of function mutations are responsible for the first cha...

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Udgivet i:Int J Mol Sci
Main Authors: Le Ribeuz, Hélène, Dumont, Florent, Ruellou, Guillaume, Lambert, Mélanie, Balliau, Thierry, Quatredeniers, Marceau, Girerd, Barbara, Cohen-Kaminsky, Sylvia, Mercier, Olaf, Yen-Nicolaÿ, Stéphanie, Humbert, Marc, Montani, David, Capuano, Véronique, Antigny, Fabrice
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582549/
https://ncbi.nlm.nih.gov/pubmed/33036472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197400
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