The Effect of Modified Porcine Surfactant Alone or in Combination with Polymyxin B on Lung Homeostasis in LPS-Challenged and Mechanically Ventilated Adult Rats

The study aimed to prove the hypothesis that exogenous surfactant and an antibiotic polymyxin B (PxB) can more effectively reduce lipopolysaccharide (LPS)-induced acute lung injury (ALI) than surfactant treatment alone, and to evaluate the effect of this treatment on the gene expression of surfactan...

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Veröffentlicht in:Molecules
Hauptverfasser: Kolomaznik, Maros, Kopincova, Jana, Nova, Zuzana, Topercerova, Juliana, Zila, Ivan, Mikolka, Pavol, Kosutova, Petra, Matasova, Katarina, Skovierova, Henrieta, Grendar, Marian, Mokra, Daniela, Calkovska, Andrea
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582504/
https://ncbi.nlm.nih.gov/pubmed/32977392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25194356
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