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Is the Secret of VDAC Isoforms in Their Gene Regulation? Characterization of Human VDAC Genes Expression Profile, Promoter Activity, and Transcriptional Regulators

VDACs (voltage-dependent anion-selective channels) are pore-forming proteins of the outer mitochondrial membrane, whose permeability is primarily due to VDACs’ presence. In higher eukaryotes, three isoforms are raised during the evolution: they have the same exon–intron organization, and the protein...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Zinghirino, Federica, Pappalardo, Xena Giada, Messina, Angela, Guarino, Francesca, De Pinto, Vito
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582299/
https://ncbi.nlm.nih.gov/pubmed/33036380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197388
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