Novel WT1 Target Genes: IL-2, IL-2RB, and IL-2RG Discovered during WT1 Silencing Using Lentiviral-Based RNAi in Myeloid Leukemia Cells

Wilms' tumor 1 (WT1) is a transcription factor which plays a major role in cell proliferation, differentiation, survival, and apoptosis. WT1 was first identified as a tumor suppressor gene in Wilms' tumor. However, overexpression of WT1 has been detected in several types of malignancy incl...

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Vydáno v:Biomed Res Int
Hlavní autoři: Dejjuy, Duangnapa, Dechsukhum, Chavaboon, Pattanapanyasat, Kovit, Noulsri, Egarit, Dissen, Gregory A, Leeanansaksiri, Wilairat
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582064/
https://ncbi.nlm.nih.gov/pubmed/33110919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/7851414
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