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Transport of ultrasmall gold nanoparticles (2 nm) across the blood–brain barrier in a six-cell brain spheroid model

The blood–brain barrier (BBB) is an efficient barrier for molecules and drugs. Multicellular 3D spheroids display reproducible BBB features and functions. The spheroids used here were composed of six brain cell types: Astrocytes, pericytes, endothelial cells, microglia cells, oligodendrocytes, and n...

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書誌詳細
出版年:Sci Rep
主要な著者: Sokolova, Viktoriya, Mekky, Gehad, van der Meer, Selina Beatrice, Seeds, Michael C., Atala, Anthony J., Epple, Matthias
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581805/
https://ncbi.nlm.nih.gov/pubmed/33093563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75125-2
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