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IVIVC for Extended Release Hydrophilic Matrix Tablets in Consideration of Biorelevant Mechanical Stress

PURPOSE: When establishing IVIVC, a special problem arises by interpretation of averaged in vivo profiles insight of considerable individual variations in term of time and number of mechanical stress events in GI-tract. The objective of the study was to investigate and forecast the effect of mechani...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Pharm Res
Hauptverfasser: Mohylyuk, Valentyn, Goldoozian, Seyedreza, Andrews, Gavin P., Dashevskiy, Andriy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581586/
https://ncbi.nlm.nih.gov/pubmed/33094368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-020-02940-7
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