Načítá se...
Extended Pharmacokinetic Model of the Intravitreal Injections of Macromolecules in Rabbits. Part 2: Parameter Estimation Based on Concentration Dynamics in the Vitreous, Retina, and Aqueous Humor
PURPOSE: To estimate the diffusion coefficients of an IgG antibody (150 kDa) and its antigen-binding fragment (Fab; 50 kDa) in the neural retina (D(ret)) and the combined retinal pigment epithelium-choroid (D(RPE-cho)) with a 3-dimensional (3D) ocular pharmacokinetic (PK) model of the rabbit eye. ME...
Uloženo v:
| Vydáno v: | Pharm Res |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Springer US
2020
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7581578/ https://ncbi.nlm.nih.gov/pubmed/33094404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-020-02946-1 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|