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Challenges in Detecting Clinically Relevant Heparin-Induced Thrombocytopenia Antibodies

Heparin-induced thrombocytopenia (HIT) is an antibody-mediated hypercoagulable state featuring high thrombosis risk and distinct pathogenesis involving immunoglobulin G-mediated platelet activation. The target of the immune response is a cationic “self” protein, platelet factor 4 (PF4), rendered ant...

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Bibliografische gegevens
Gepubliceerd in:Hamostaseologie
Hoofdauteur: Warkentin, Theodore E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Georg Thieme Verlag KG 2020
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581458/
https://ncbi.nlm.nih.gov/pubmed/33091948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/a-1223-3329
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