Transient Transfection of the Respiratory Epithelium with Gamma Interferon for Host-Directed Therapy in Pulmonary Tuberculosis

Nebulized gamma interferon (IFN-γ) protein has been studied for clinical safety and efficacy against pulmonary tuberculosis (TB). The protein is expensive, requires a cold chain, and is difficult to deploy in limited-resource, high-incidence settings. We generated a preclinical proof of concept (PoC...

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Veröffentlicht in:Mol Ther Nucleic Acids
Hauptverfasser: Bharti, Reena, Srivastava, Ashish, Roy, Trisha, Verma, Khushboo, Reddy, D.V. Siva, Shafi, Hasham, Verma, Sonia, Raman, Sunil K., Singh, Amit K., Singh, Jyotsna, Ray, Lipika, Misra, Amit
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2020
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581375/
https://ncbi.nlm.nih.gov/pubmed/33110704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.10.023
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