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Functional Genomics in Pancreatic β Cells: Recent Advances in Gene Deletion and Genome Editing Technologies for Diabetes Research

The inheritance of variants that lead to coding changes in, or the mis-expression of, genes critical to pancreatic beta cell function can lead to alterations in insulin secretion and increase the risk of both type 1 and type 2 diabetes. Recently developed clustered regularly interspaced short palind...

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Bibliografiske detaljer
Udgivet i:Front Endocrinol (Lausanne)
Main Authors: Hu, Ming, Cherkaoui, Ines, Misra, Shivani, Rutter, Guy A.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7580382/
https://ncbi.nlm.nih.gov/pubmed/33162936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2020.576632
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