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Establishment and Use of Patient-Derived Xenograft Models for Drug Testing in Head and Neck Squamous Cell Carcinoma

This protocol provides the steps required for the establishment of patient-derived xenograft (PDX) tumors for head and neck squamous cell carcinomas (HNSCCs) and their utility in examining drug responses. PDXs recapitulate the heterogeneity observed in the corresponding human tumors, which makes the...

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Detalhes bibliográficos
Publicado no:STAR Protoc
Main Authors: Karamboulas, Christina, Meens, Jalna, Ailles, Laurie
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7580210/
https://ncbi.nlm.nih.gov/pubmed/33111077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2020.100024
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