CXCL1 contributes to IL-6 expression in osteoarthritis and rheumatoid arthritis synovial fibroblasts by CXCR2, c-Raf, MAPK, and AP-1 pathway

BACKGROUND: Osteoarthritis (OA) and rheumatoid arthritis (RA) are common joint disorders that are considered to be different diseases due to their unique molecular mechanisms and pathogenesis. Chemokines and their corresponding receptors have been well characterized in RA progression, but less so in...

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Bibliographic Details
Published in:Arthritis Res Ther
Main Authors: Hou, Sheng-Mou, Chen, Po-Chun, Lin, Chieh-Mo, Fang, Mei-Ling, Chi, Miao-Ching, Liu, Ju-Fang
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7580030/
https://ncbi.nlm.nih.gov/pubmed/33087182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-020-02331-8
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