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Proanthocyanidin B2 inhibits proliferation and induces apoptosis of osteosarcoma cells by suppressing the PI3K/AKT pathway

Osteosarcoma (OS) is the most common primary malignant bone tumour in children and adolescents. The long‐term survival rate of OS patients is stubbornly low mainly due to the chemotherapy resistance. We therefore aimed to investigate the antitumoral effects and underlying mechanisms of proanthocyani...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Wu, Xinbo, Yu, Haiyang, Zhou, Haichao, Li, Zihua, Huang, Hui, Xiao, Fajiao, Xu, Shaochen, Yang, Yunfeng
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7579710/
https://ncbi.nlm.nih.gov/pubmed/32914567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15818
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