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LIGHT aggravates sepsis‐associated acute kidney injury via TLR4‐MyD88‐NF‐κB pathway

Sepsis‐associated acute kidney injury (SA‐AKI) is a common clinical critical care syndrome. It has received increasing attention due to its high morbidity and mortality; however, its pathophysiological mechanisms remain elusive. LIGHT, the 14th member of the tumour necrosis factor (TNF) superfamily...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Zhong, Yu, Wu, Shun, Yang, Yan, Li, Gui‐qing, Meng, Li, Zheng, Quan‐you, Li, You, Xu, Gui‐lian, Zhang, Ke‐qin, Peng, Kan‐fu
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7579683/
https://ncbi.nlm.nih.gov/pubmed/32881263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15815
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