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Pomegranate Juice does not Affect the Bioavailability of Cyclosporine in Healthy Thai Volunteers

BACKGROUND: It is still controversial whether pomegranate causes drug interactions. Pomegranate juice has been shown to inhibit CYP3A in-vitro and animal studies. The co-administration of pomegranate juice with cyclosporine, a narrow therapeutic drug that is the substrate of CYP3A, might lead to dru...

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Detalhes bibliográficos
Publicado no:Curr Clin Pharmacol
Main Authors: Anlamlert, Wirin, Sermsappasuk, Pakawadee
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7579232/
https://ncbi.nlm.nih.gov/pubmed/31924158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1574884715666200110153125
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