Inhibition of CPT2 exacerbates cardiac dysfunction and inflammation in experimental endotoxaemia

The suppression of energy metabolism is one of cornerstones of cardiac dysfunction in sepsis/endotoxaemia. To investigate the role of fatty acid oxidation (FAO) in the progression of inflammation‐induced cardiac dysfunction, we compared the effects of FAO‐targeting compounds on mitochondrial and car...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Makrecka‐Kuka, Marina, Korzh, Stanislava, Videja, Melita, Vilskersts, Reinis, Sevostjanovs, Eduards, Zharkova‐Malkova, Olga, Arsenyan, Pavel, Kuka, Janis, Dambrova, Maija, Liepinsh, Edgars
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7578905/
https://ncbi.nlm.nih.gov/pubmed/32896106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15809
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