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Emodin inhibiting neutrophil elastase‐induced epithelial‐mesenchymal transition through Notch1 signalling in alveolar epithelial cells

The transition of alveolar type II epithelial cells into fibroblasts has been reported to cause and/or aggravate pulmonary fibrosis (PF), which is characterized by fibroblast proliferation, an enhanced production and accumulation of ECM (extracellular matrix), alveolar wall damage and functional cap...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Zhou, Linshui, Gao, Rundi, Hong, Huihua, Li, Xiaojuan, Yang, Jia, Shen, Wei, Wang, Zhen, Yang, Junchao
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7578861/
https://ncbi.nlm.nih.gov/pubmed/32935466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15827
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