Chronotherapy with a Renin-angiotensin System Inhibitor Ameliorates Renal Damage by Suppressing Intrarenal Renin-angiotensin System Activation

OBJECTIVE: The intrarenal renin-angiotensin system (RAS) is activated in chronic kidney disease (CKD) patients and is not suppressed at night in CKD patients showing nocturnal hypertension, contributing to renal damage. Furthermore, changes in RAS inhibitor administration from morning to evening, na...

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Vydáno v:Intern Med
Hlavní autoři: Aoki, Taro, Ohashi, Naro, Isobe, Shinsuke, Ishigaki, Sayaka, Matsuyama, Takashi, Sato, Taichi, Fujikura, Tomoyuki, Kato, Akihiko, Miyajima, Hiroaki, Yasuda, Hideo
Médium: Artigo
Jazyk:Inglês
Vydáno: The Japanese Society of Internal Medicine 2020
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7578605/
https://ncbi.nlm.nih.gov/pubmed/32938851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2169/internalmedicine.4243-19
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