Caricamento...
CHIP mutations affect the heat shock response differently in human fibroblasts and iPSC-derived neurons
C-terminus of HSC70-interacting protein (CHIP) encoded by the gene STUB1 is a co-chaperone and E3 ligase that acts as a key regulator of cellular protein homeostasis. Mutations in STUB1 cause autosomal recessive spinocerebellar ataxia type 16 (SCAR16) with widespread neurodegeneration manifesting as...
Salvato in:
| Pubblicato in: | Dis Model Mech |
|---|---|
| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Company of Biologists Ltd
2020
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7578354/ https://ncbi.nlm.nih.gov/pubmed/33097556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.045096 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|