Risk of Transmissibility From Neurodegenerative Disease-Associated Proteins: Experimental Knowns and Unknowns

Recent studies in animal models demonstrate that certain misfolded proteins associated with neurodegenerative diseases can support templated misfolding of cognate native proteins, to propagate across neural systems, and to therefore have some of the properties of classical prion diseases like Creutz...

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Publié dans:J Neuropathol Exp Neurol
Auteurs principaux: Asher, David M, Belay, Ermias, Bigio, Eileen, Brandner, Sebastian, Brubaker, Scott A, Caughey, Byron, Clark, Brychan, Damon, Inger, Diamond, Marc, Freund, Michelle, Hyman, Bradley T, Jucker, Mathias, Keene, C Dirk, Lieberman, Andrew P, Mackiewicz, Miroslaw, Montine, Thomas J, Morgello, Susan, Phelps, Creighton, Safar, Jiri, Schneider, Julie A, Schonberger, Lawrence B, Sigurdson, Christina, Silverberg, Nina, Trojanowski, John Q, Frosch, Matthew P
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Review Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577514/
https://ncbi.nlm.nih.gov/pubmed/33000167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlaa109
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