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Advances in potential treatment options for myeloproliferative neoplasm associated myelofibrosis

INTRODUCTION: The Janus kinase (JAK)1/2 inhibitor ruxolitinib provides rapid, sustained and often dramatic benefits to patients with myelofibrosis, inducing spleen shrinkage and ameliorating symptoms, and improves survival. However, the drug has little effect on the underlying bone marrow fibrosis o...

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Bibliographic Details
Published in:Expert Opin Orphan Drugs
Main Author: Bose, Prithviraj
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577425/
https://ncbi.nlm.nih.gov/pubmed/33094033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21678707.2019.1664900
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