Effect of Tocilizumab vs Standard Care on Clinical Worsening in Patients Hospitalized With COVID-19 Pneumonia: A Randomized Clinical Trial

IMPORTANCE: The coronavirus disease 2019 (COVID-19) pandemic is threatening billions of people worldwide. Tocilizumab has shown promising results in retrospective studies in patients with COVID-19 pneumonia with a good safety profile. OBJECTIVE: To evaluate the effect of early tocilizumab administra...

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Detalhes bibliográficos
Publicado no:JAMA Intern Med
Main Authors: Salvarani, Carlo, Dolci, Giovanni, Massari, Marco, Merlo, Domenico Franco, Cavuto, Silvio, Savoldi, Luisa, Bruzzi, Paolo, Boni, Fabrizio, Braglia, Luca, Turrà, Caterina, Ballerini, Pier Ferruccio, Sciascia, Roberto, Zammarchi, Lorenzo, Para, Ombretta, Scotton, Pier Giorgio, Inojosa, Walter Omar, Ravagnani, Viviana, Salerno, Nicola Duccio, Sainaghi, Pier Paolo, Brignone, Alessandro, Codeluppi, Mauro, Teopompi, Elisabetta, Milesi, Maurizio, Bertomoro, Perla, Claudio, Norbiato, Salio, Mario, Falcone, Marco, Cenderello, Giovanni, Donghi, Lorenzo, Del Bono, Valerio, Colombelli, Paolo Luigi, Angheben, Andrea, Passaro, Angelina, Secondo, Giovanni, Pascale, Renato, Piazza, Ilaria, Facciolongo, Nicola, Costantini, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2021
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577199/
https://ncbi.nlm.nih.gov/pubmed/33080005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamainternmed.2020.6615
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