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Activities of Cefiderocol with Simulated Human Plasma Concentrations against Carbapenem-Resistant Gram-Negative Bacilli in an In Vitro Chemostat Model

Activities of cefiderocol under simulated human plasma concentrations at the recommended dosing regimen of 2 g every 8 h with a 3-h infusion were evaluated using an in vitro chemostat model. Against a total of 6 meropenem-resistant Gram-negative strains with cefiderocol MICs of 0.5 to 4 μg/ml, inclu...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Matsumoto, Shuhei, Kanazawa, Sachi, Sato, Takafumi, Yamano, Yoshinori
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577172/
https://ncbi.nlm.nih.gov/pubmed/32900685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01128-20
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