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Identification of Small-Molecule Inhibitors Targeting Porphyromonas gingivalis Interspecies Adherence and Determination of Their In Vitro and In Vivo Efficacies

Porphyromonas gingivalis is one of the primary causative agents of periodontal disease and initially colonizes the oral cavity by adhering to commensal streptococci. Adherence requires the interaction of a minor fimbrial protein (Mfa1) of P. gingivalis with streptococcal antigen I/II (AgI/II). Our p...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Roky, Mohammad, Tan, Jinlian, Sztukowska, Maryta N., Trent, John O., Demuth, Donald R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577153/
https://ncbi.nlm.nih.gov/pubmed/32816725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00884-20
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