DESTINATION: a phase 3, multicentre, randomized, double-blind, placebo-controlled, parallel-group trial to evaluate the long-term safety and tolerability of tezepelumab in adults and adolescents with severe, uncontrolled asthma

BACKGROUND: Tezepelumab is a human monoclonal antibody that blocks the activity of the epithelial cytokine thymic stromal lymphopoietin. The efficacy, safety and oral corticosteroid-sparing potential of tezepelumab are being investigated in two ongoing, phase 3, randomized, double-blind, placebo-con...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Respir Res
Hauptverfasser: Menzies-Gow, Andrew, Ponnarambil, Sandhia, Downie, John, Bowen, Karin, Hellqvist, Åsa, Colice, Gene
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Study Protocol
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576983/
https://ncbi.nlm.nih.gov/pubmed/33087119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-020-01541-7
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