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Ustekinumab dose escalation improves clinical responses in refractory Crohn’s disease

BACKGROUND: Clinicians often utilize off-label dose escalation of ustekinumab (UST) in Crohn’s disease (CD) patients with disease refractory to standard dosing. Previous studies report mixed results with dose escalation of UST. METHODS: A retrospective observational study of 143 adult patients with...

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Gepubliceerd in:Therap Adv Gastroenterol
Hoofdauteurs: Haider, Syedreza A., Yadav, Abhijeet, Perry, Courtney, Su, Leon, Akanbi, Olalekan, Kudaravalli, Praneeth, Tripathi, Nishant, Hashim, Mahmoud A., Abdelsalam, Mohammed, Hussein, Mohamed, Elkheshen, Ahmed, Patel, Vihang, Ali, Saad Emhmed, Lamb, Latoya, Ingram, Karen, Mayne, Casie, Stuffelbeam, Amy B., Flomenhoft, Deborah, Stromberg, Arnold, Barrett, Terrence A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: SAGE Publications 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576911/
https://ncbi.nlm.nih.gov/pubmed/33133239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756284820959245
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