Hypoxia-autophagy axis induces VEGFA by peritoneal mesothelial cells to promote gastric cancer peritoneal metastasis through an integrin α5-fibronectin pathway

BACKGROUND: Peritoneal metastasis (PM) is an important pathological process in the progression of gastric cancer (GC). The metastatic potential of tumor and stromal cells is governed by hypoxia, which is a key molecular feature of the tumor microenvironment. Mesothelial cells also participate in thi...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Exp Clin Cancer Res
Autori principali: Wang, Xiaoxun, Che, Xiaofang, Yu, Yang, Cheng, Yu, Bai, Ming, Yang, Zichang, Guo, Qiqiang, Xie, Xiaochen, Li, Danni, Guo, Min, Hou, Kezuo, Guo, Wendong, Qu, Xiujuan, Cao, Liu
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576728/
https://ncbi.nlm.nih.gov/pubmed/33081836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01703-x
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