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Drug repurposing in Raynaud's phenomenon through adverse event signature matching in the World Health Organization pharmacovigilance database

AIMS: Several pharmacological treatments are recommended for Raynaud's phenomenon (RP) secondary to systemic sclerosis, but they only have modest efficacy. A way to efficiently identify new drugs is drug repurposing, which can be based on signature matching. The signature could be derived from...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Zaza, Putkaradze, Matthieu, Roustit, Jean‐Luc, Cracowski, Charles, Khouri
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576623/
https://ncbi.nlm.nih.gov/pubmed/32337731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14322
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