Hypoglycemia-Sensing Neurons of the Ventromedial Hypothalamus Require AMPK-Induced Txn2 Expression but Are Dispensable for Physiological Counterregulation

The ventromedial nucleus of the hypothalamus (VMN) is involved in the counterregulatory response to hypoglycemia. VMN neurons activated by hypoglycemia (glucose-inhibited [GI] neurons) have been assumed to play a critical although untested role in this response. Here, we show that expression of a do...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Diabetes
Prif Awduron: Quenneville, Simon, Labouèbe, Gwenaël, Basco, Davide, Metref, Salima, Viollet, Benoit, Foretz, Marc, Thorens, Bernard
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Diabetes Association 2020
Pynciau:
Metabolism
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576557/
https://ncbi.nlm.nih.gov/pubmed/32839348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db20-0577
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