Profibrotic Circulating Proteins and Risk of Early Progressive Renal Decline in Patients With Type 2 Diabetes With and Without Albuminuria

OBJECTIVE: The role of fibrosis in early progressive renal decline in type 2 diabetes is unknown. Circulating WFDC2 (WAP four-disulfide core domain protein 2) and matrix metalloproteinase 7 (MMP-7; Matrilysin) are postulated to be biomarkers of renal fibrosis. This study examined an association of c...

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Sparad:
Bibliografiska uppgifter
I publikationen:Diabetes Care
Huvudupphovsmän: Ihara, Katsuhito, Skupien, Jan, Kobayashi, Hiroki, Md Dom, Zaipul I., Wilson, Jonathan M., O’Neil, Kristina, Badger, Hannah S., Bowsman, Lenden M., Satake, Eiichiro, Breyer, Matthew D., Duffin, Kevin L., Krolewski, Andrzej S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Diabetes Association 2020
Ämnen:
Pathophysiology/Complications
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576423/
https://ncbi.nlm.nih.gov/pubmed/32887710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc20-0630
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