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Paradoxical risk of reduced fertility after exposure of prepubertal mice to vincristine or cyclophosphamide at low gonadotoxic doses in humans

Cancer treatment can have long-term side effects in cured patients and infertility is one of them. Given the urgency of diagnosis in children with cancer, the toxicity of treatments on the gonad was overshadowed for a long time. In the present study, prepubertal mice were treated by vincristine or c...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Delessard, Marion, Saulnier, Justine, Dumont, Ludovic, Rives-Feraille, Aurélie, Rives, Nathalie, Rondanino, Christine
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576200/
https://ncbi.nlm.nih.gov/pubmed/33082498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74862-8
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