MLH1 single-nucleotide variant in circulating tumor DNA predicts overall survival of patients with hepatocellular carcinoma

Liquid biopsy can provide a strong basis for precision medicine. We aimed to identify novel single-nucleotide variants (SNVs) in circulating tumor DNA (ctDNA) in patients with hepatocellular carcinoma (HCC). Deep sequencing of plasma-derived ctDNA from 59 patients with HCC was performed using a pane...

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Udgivet i:Sci Rep
Main Authors: Kim, Soon Sun, Eun, Jung Woo, Choi, Ji-Hye, Woo, Hyun Goo, Cho, Hyo Jung, Ahn, Hye Ri, Suh, Chul Won, Baek, Geum Ok, Cho, Sung Won, Cheong, Jae Youn
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576198/
https://ncbi.nlm.nih.gov/pubmed/33082400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74494-y
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