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Ligustilide alleviates podocyte injury via suppressing the SIRT1/NF-κB signaling pathways in rats with diabetic nephropathy

BACKGROUND: Diabetic nephropathy (DN) is one of the common chronic microvascular complications of diabetes, and podocyte injury and dysfunction are strictly related to the pathogenesis of DN. Studies have shown that ligustilide (LIG) has anti-inflammatory, antioxidant, and anti-apoptotic activities....

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Detalhes bibliográficos
Publicado no:Ann Transl Med
Main Authors: Xu, Feng, Ye, Zi, Tao, Shuo, Liu, Wangshu, Su, Jianbing, Fang, Xingxing, Wang, Xueqin
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576076/
https://ncbi.nlm.nih.gov/pubmed/33241003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-20-5811
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