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Spinal interleukin-6 contributes to central sensitisation and persistent pain hypersensitivity in a model of juvenile idiopathic arthritis

Pain is the most debilitating symptom in juvenile idiopathic arthritis. As pain correlates poorly to the extent of joint pathology, therapies that control joint inflammation are often inadequate as analgesics. We test the hypothesis that juvenile joint inflammation leads to sensitisation of nocicept...

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Detalhes bibliográficos
Publicado no:Brain Behav Immun
Main Authors: Kwok, Charlie H.T., Learoyd, Annastazia E, Canet-Pons, Julia, Trang, Tuan, Fitzgerald, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7575902/
https://ncbi.nlm.nih.gov/pubmed/32791212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2020.08.004
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