The Double-Edge Sword of Autophagy in Cancer: From Tumor Suppression to Pro-tumor Activity

During tumorigenesis, cancer cells are exposed to a wide variety of intrinsic and extrinsic stresses that challenge homeostasis and growth. Cancer cells display activation of distinct mechanisms for adaptation and growth even in the presence of stress. Autophagy is a catabolic mechanism that aides i...

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Bibliographic Details
Published in:Front Oncol
Main Authors: Chavez-Dominguez, Rodolfo, Perez-Medina, Mario, Lopez-Gonzalez, Jose S., Galicia-Velasco, Miriam, Aguilar-Cazares, Dolores
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7575731/
https://ncbi.nlm.nih.gov/pubmed/33117715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.578418
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