14,15-Epoxyeicosatrienoic Acid Alleviates Pathology in a Mouse Model of Alzheimer's Disease

Alzheimer's disease (AD) is the leading cause of late-onset dementia, and there exists an unmet medical need for effective treatments for AD. The accumulation of neurotoxic amyloid-β (Aβ) plaques contributes to the pathophysiology of AD. EPHX2 encoding soluble epoxide hydrolase (sEH)—a key enzy...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Chen, Wenjun, Wang, Mengyao, Zhu, Minzhen, Xiong, Wenchao, Qin, Xihe, Zhu, Xinhong
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7574654/
https://ncbi.nlm.nih.gov/pubmed/32973044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1246-20.2020
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