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Core regulatory circuitries in defining cancer cell identity across the malignant spectrum
Gene expression programmes driving cell identity are established by tightly regulated transcription factors that auto- and cross-regulate in a feed-forward manner, forming core regulatory circuitries (CRCs). CRC transcription factors create and engage super-enhancers by recruiting acetylation writer...
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| Publicat a: | Open Biol |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Royal Society
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7574545/ https://ncbi.nlm.nih.gov/pubmed/32634370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.200121 |
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